Reprinted as posted on Swine in Minnesota blog May 2, 2025
Key points:
Key points:
- Clinical re-breaks of PRRSV on sow farms are a frustrating reality for producers and practitioners and occur despite consistent use of modified live vaccines (MLV).
- 13 re-break events on 12 farms were identified from production and diagnostic data and were analyzed at the whole genome level.
- Numerous amino acid sites on structural proteins were observed to change frequently between the primary and secondary outbreaks. This includes sites previously associated with escape from serum neutralization or to be positively selected, and sites known to be accessible to antibodies.
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